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推薦這個網站!每天可以抽一點時間練英文聽力,外加接收科學知識也不錯!

今天聽的是:

In Mice Anti-Inflammatories Ameliorate Medical Marijuana's Memory Mishaps(Listen to this Podcast)

Medical marijuana helps treat disorders such as chronic pain, nausea and seizures. Unfortunately, it can also...um...oh yeah, it can also impair memory and learning. But a new study suggests we can prevent this side effect with easily available medication.

The problem stems from the hippocampus, the brain region responsible for memory formation. So scientists exposed mice to THC, the psychoactive chemical in cannabis, and then looked at their brains. They noticed that the hippocampi of the treated mice produced higher levels of an enzyme called COX-2. When the researchers administered drugs that reduced levels of COX-2, the memory problems disappeared as well. As did some neuron damage.

But protecting the brain against memory loss did not seem to stop the positive effects of marijuana.

The scientists used cannabis to treat a mouse model of Alzheimer's disease. Whether or not they inhibited COX-2, pot appeared to be beneficial. The work is in the journal Cell. [Chen et al., Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signaling]

Drugs that block COX-2 include anti-inflammatories, such as over-the-counter painkiller ibuprofen. But before you start self-medicating, you might want to wait for confirmation in people.

—Sophie Bushwick

[The above text is a transcript of this podcast.]

 

 我猜測文意大概是這樣吧( ̄▽ ̄)

藥用大麻可以治療一些疾病,但是會有副作用降低記憶力和學習力,有研究指出可以靠容易取得的藥物去防範。

問題點發生在腦中掌管記憶的海馬體(hippocampus),研究員提供給老鼠THC, the psychoactive chemical in cannabis(也是大麻吧),並觀察老鼠的腦袋,發現製造出過量COX-2酵素酶,若提供藥物降低COX-2,記憶問題解決,但也損傷到神經元細胞。-_-#

雖然保護大腦記憶不會損傷,但也似乎並沒有降低大麻的正面效益(But protecting the brain against memory loss did not seem to stop the positive effects of marijuana.這句一開始不太懂為什麼會用stop,是詢問大家後歸納出比較合理的意思 )

運用在Alzheimer's disease的老鼠身上,有正面效益,文章出自journal Cell.

阻擋COX-2酵素酶的藥是anti-inflammatories, 例如 over-the-counter painkiller ibuprofen(不知道是什麼...),但在你試圖嘗試自己去買藥來吃之前,最好再等一下人體測試的結果.



 

 

 

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